Circadian disruptions in an animal model of Alzheimer’s are mitigated by time-restricted eating

Alzheimer’s disease is a debilitating neurodegenerative disorder affecting millions of individuals and their families worldwide. With no cure in sight, researchers are continually exploring innovative approaches to alleviate the symptoms and slow the progression of this devastating disease. One emerging avenue of investigation involves addressing the disruption of circadian rhythms, the body’s internal biological clock, … Read more

6 Great Techniques to Speed Up Body Fat Loss – BOXROX

In today’s fast-paced world, where health and fitness have become paramount concerns, the significance of body fat loss cannot be overstated. Excess body fat not only affects our physical appearance but also poses serious risks to our overall health and well-being. From cardiovascular diseases to metabolic disorders, carrying excess fat can lead to a plethora … Read more

Captain Kate! Princess of Wales sits in the cockpit of a Royal Navy helicopter and tries out a flight simulator on visit to an air base in Somerset

The Princess of Wales was in the captain’s seat on her visit to a Royal Navy air base this afternoon as she tried her hand at a helicopter’s flight simulator. Kate, 41, donned a £549 black blazer from Holland Cooper which she has worn previously, with gold button detailing, paired with trousers and £650 black … Read more

Drug delivery systems for CRISPR-based genome editors

Li, Y., Glass, Z., Huang, M., Chen, Z. Y. & Xu, Q. Ex vivo cell-based CRISPR/Cas9 genome editing for therapeutic applications. Biomaterials 234, 119711 (2020). Article  CAS  PubMed  PubMed Central  Google Scholar  Dong, W. & Kantor, B. Lentiviral vectors for delivery of gene-editing systems based on CRISPR/Cas: current state and perspectives. Viruses 13, 1288 (2021). … Read more

Will Slovakia’s Elections Signal War Fatigue?

Slovakia will hold elections at the end of this month, just over thirty years after securing an elusive permanent independence. Unelected governments have led the country for nearly a year, as former Prime Minister Eduard Heger resigned following a vote of no-confidence in December 2022, and the country’s president appointed a caretaker “technocratic” government in … Read more

Alzheimer’s Expert Explains How Genetic Mutations Can Slow The Disease : ScienceAlert

Diseases that run in families usually have genetic causes. Some are genetic mutations that directly cause the disease if inherited. Others are risk genes that affect the body in a way that increases the chance someone will develop the disease. In Alzheimer’s disease, genetic mutations in any of three specific genes can cause the disease, … Read more

Taiwan’s Path Between Extremes | Foreign Affairs

Taiwan is recognized around the world for its economic development and democratic achievements, its cutting-edge industries, and its vibrant civil society. In recent years, however, this island of 23 million people has been described in international media in darker terms. Some have called it a flashpoint that could start the next world war or even, … Read more

In Wagner Group’s biggest African base, Russia to control mercenaries

September 18, 2023 at 2:00 a.m. EDT A statue representing Russian instructors belonging to the Wagner mercenary company in Bangui, Central African Republic, on Sept. 5. (Barbara Debout for The Washington Post) Comment on this storyComment BANGUI, Central African Republic — Since the mercenaries of Russia’s notorious Wagner Group first arrived here five years ago, … Read more

Russia Running Out of Pretty Much Everything as Sanctions Bite

Sanctions imposed on Russia by Western nations in response to President Vladimir Putin’s full-scale invasion of Ukraine have contributed to a nationwide shortage of fuel, while some items typically readily available are now in short supply. Since the full-scale invasion of Ukraine began in February 2022, Russia has become subject to more than 13,000 restrictions. … Read more