CRISPR screens decode cancer cell pathways that trigger γδ T cell detection

[ad_1] Silva-Santos, B., Serre, K. & Norell, H. γδ T cells in cancer. Nat. Rev. Immunol. 15, 683–691 (2015). Article  CAS  PubMed  Google Scholar  Sebestyen, Z., Prinz, I., Déchanet-Merville, J., Silva-Santos, B. & Kuball, J. Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies. Nat. Rev. Drug Discov. 19, 169–184 (2020). Article  … Read more

Hypothalamic GABRA5-positive neurons control obesity via astrocytic GABA

[ad_1] Kong, D. et al. GABAergic RIP–Cre neurons in the arcuate nucleus selectively regulate energy expenditure. Cell 151, 645–657 (2012). Article  CAS  PubMed  PubMed Central  Google Scholar  Thaler, J. P. et al. Obesity is associated with hypothalamic injury in rodents and humans. J. Clin. Invest. 122, 153–162 (2012). Article  CAS  PubMed  Google Scholar  Flament-Durand, J. … Read more

Daily aspirin after a heart attack can reduce the risk of future events, study finds

[ad_1] For people who have previously had a heart attack, taking a daily aspirin could reduce their risk of a repeat cardiac event or stroke, according to a recent Danish study. The findings were presented at the ESC Congress 2023 in Amsterdam this week. “Our findings support current clinical guidelines on aspirin therapy following myocardial … Read more

Symptoms 24 hours before may differ for men and women

[ad_1] Share on PinterestA study found that men and women experience different symptoms before a cardiac arrest. Carol Yepes/Getty Images Of the more than 356,000 cardiac arrests in the United States each year, 90% are fatal. While there are some known signs of sudden cardiac arrest, it usually occurs without warning. Researchers from the Smidt … Read more

Which one is better for you?

[ad_1] Lifestyle By Perri Ormont Blumberg, Fox News August 31, 2023 | 1:56pm When it comes to food debates, some people may be interested in the health score on a particular sandwich staple: Bread. If you’re wondering about white bread, whole wheat, or whole grain bread which may be dubbed the “better choice,”  experts are offering answers. … Read more

Should You Take Magnesium and Vitamin D Together?

[ad_1] Valentina Barreto/Stocksy Taking magnesium and vitamin D supplements together has become a buzzy trend online in recent weeks, but people don’t always need to take both supplements to see health benefits, experts said. On TikTok, users are extolling the benefits of magnesium supplements in particular, claiming they can help with a variety of health … Read more

Brain’s Weight Switch Found: Eat What You Want, Lose Weight With New Treatment

[ad_1] Summary: A revolutionary discovery reveals that astrocytes, star-shaped cells in the brain, play a key role in regulating fat metabolism and obesity. These cells act on a cluster of neurons, known as the GABRA5 cluster, effectively acting as a “switch” for weight regulation. A new drug, KDS2010, has been shown to facilitate weight loss … Read more